Profil Metabolit Ekstrak n-Heksan Kulit Batang Faloak (Sterculia quadrifida R.Br.) Berdasarkan Analisis GC-MS
DOI:
https://doi.org/10.63004/hrji.v4i6.1595Keywords:
sterculia quadrifida, ekstrak n-Heksan, kulit batang, profil metabolit, GC-MSAbstract
Faloak (Sterculia quadrifida R.Br.) merupakan tanaman obat khas Pulau Rote, Nusa Tenggara Timur, yang bagian kulit batangnya banyak dimanfaatkan dalam pengobatan tradisional, namun penelitian sebelumnya masih berfokus pada ekstrak polar sehingga profil senyawa nonpolar belum banyak diungkap. Penelitian ini bertujuan untuk mengetahui profil metabolit ekstrak n-heksan kulit batang faloak asal Pulau Rote menggunakan metode Gas Chromatography-Mass Spectrometry (GC-MS). Penelitian bersifat deskriptif kualitatif; sampel diekstraksi melalui metode maserasi menggunakan pelarut n-heksan, kemudian dianalisis menggunakan instrumen Thermo Fisher Trace 1610 GC-ISQ 7610 dengan kolom kapiler TG-5MS, dan senyawa diidentifikasi berdasarkan basis data NIST/EPA/NIH Mass Spectral Library. Hasil ekstraksi menghasilkan rendemen sebesar 0,025% dengan 202 komponen total, di mana 12 senyawa dominan didominasi oleh golongan asam lemak dan ester asam lemak, dengan kadar relatif tertinggi pada trans-13-Octadecenoic acid (7,67%) dan n-Hexadecanoic acid (4,67%), sementara golongan alkana dan hidrokarbon siklik terdeteksi pada waktu retensi awal dengan kadar kumulatif lebih dari 28%. Profil metabolit ini menunjukkan bahwa ekstrak n-heksan kulit batang faloak berpotensi dikembangkan sebagai kandidat bahan baku obat alami, meskipun seluruh potensi aktivitas farmakologi masih bersifat referensial dan memerlukan pembuktian lebih lanjut melalui pengujian bioaktivitas secara langsung.
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